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Lipid Nanoparticle Program

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Lipid Nanoparticle Program

Glycolipid receptors typically found on the cell membrane surface can be incorporated into synthetic HDL to prevent pathogens such as cholera toxin from binding to healthy cells.

The goals of the Lipid Nanoparticle Program (LNP) are to develop methods to assess the diverse properties and functions of HDL and discover dietary strategies for improving them. HDL is known for its positive effects on cardiovascular health. HDL lipoproteins are now recognized as nanoparticles of the innate immune system whose actions are vital in preventing blood-borne infections and intoxications. LNP researchers are using the tools of nanoscience to isolate, characterize and reformulate HDL as the path to the next generation of health assessment technologies, HDL-based therapies, and food-based solutions for improving HDL function. 

Current Projects

 

News
CAES Webnews
Students Nancy Rivera and Deborah Gho Present at the American Chemical Society Conference Apr 16, 2013

Students from the Foods for Health Institute’s Undergraduate Mentorship program presented at the American Chemical Society’s (ACS) 245th annual conference. The ACS “Chemistry of Energy and Food” conference took place in New Orleans from April 7 – 11, 2013.

CAES Webnews
Nanoscience Reapplied: A Breakthrough In Personalized Nutrition? Jun 10, 2010

The Foods for Health Institute has launching a translational research program applying the technologies of nanoscience to understanding the structures and functions of lipid particles. Within this program are projects developing: new technologies for the measurement of HDL function, composition, and structure, new HDL diagnostics that will lead to novel dietary approaches to decrease heart disease risk in individuals, an understanding of the functions of the newly identified lipid particles in human milk. FFHI director, Dr. Bruce German, heads the new Lipid Nanoparticle Program and describes its goals.

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